At the end of this activity, participants should be able to: 

ALLERGY PRACTICE: 
•    Describe the basic structure and elements of a GRADE document
•    Detail methods used to critically appraise evidence, rate its quality, and formulate a recommendation
•    Discuss how to translate evidence to a decision, assess its potential impact and implementation needs
ANAPHYLAXIS:
•    Describe how epinephrine works to stabilize the mast cell
•    Detail anaphylaxis epidemiology, PK/PD, and describe how route of administration affects absorbance and hemodynamics
•    Discuss current evidence gaps and updated practice guidelines 
ARTIFICIAL INTELLIGENCE IN CLINICAL MEDICINE 
•    Describe what artificial intelligence (AI) is and how it works. 
•    Discuss how AI relates to medicine, including key limitations and caveats associated with its use.
ASTHMA:
•    Discuss the prevalence of small airway dysfunction and how to how to measure it in clinical practice 
•    Discuss the pathobiology of small airway inflammation and remodeling in asthma and COPD
•    Recognize the clinical patterns and diagnostic challenges of recurrent wheeze and early childhood asthma and implement current guideline-directed therapies for preschool asthma
•    Evaluate the role of emerging tools from biomarkers to biologic agents
•    Discuss the functions of the airway epithelium and its role in host defense, particularly innate immune function, and in immune system reprogramming
ATOPIC DERMATITIS:
•    Identify environmental exposures associated with atopic dermatitis flare risk
•    Apply the HELPSS AD mnemonic to counsel patients on feasible nonprescription mitigation strategies for atopic dermatitis
•    Evaluate the evidence supporting microbiome and lipidcentric interventions in AD
EOSINOPHILIC ESOPHAGITIS:
•    Apply consensus diagnostic criteria to patient care in eosinophilic esophagitis (EoE). 
•    Incorporate an understanding of the mechanisms driving esophageal remodeling, its clinical manifestations, and appropriate tests to assess remodeling in order to devise an appropriate care paradigm for EoE patients.
EUSTACHIAN TUBE DYSFUNCTION:
•    Identify clinical presentations and diagnostic criteria that distinguish obstructive and patulous Eustachian tube dysfunction
•    Apply evidence-based medical and procedural management strategies for patients with persistent Eustachian tube dysfunction
•    Incorporate indications for referral and emerging interventions, such as balloon dilation, into clinical decision-making for complex or refractory cases
FOOD ALLERGY:
•    Explain thresholds and eliciting doses and how they inform risk assessment in food allergy management
•    Apply structured food ladders to support safe, progressive dietary advancement in children with IgE-mediated food allergies
•    Integrate threshold-based and ladder-guided approaches into individualized treatment plans using case-based scenarios, while addressing caregiver concerns and safety monitoring
•    Describe the epidemiology, risk factors, diagnosis, and management of IgE-mediated food allergy in adulthood, including factors associated with breach of oral tolerance
•    Identify emerging treatment approaches for hereditary angioedema (HAE)
•    Describe how IgE-mediated immune sensing of food allergens engages neuroimmune pathways that influence behavior and emotional states
•    Explain the roles of mast cells, lipid mediators, and key brain regions (e.g., central amygdala) in shaping behavioral responses to food allergens
•    Differentiate immune-driven behavioral responses in food allergy from infection-induced sickness behaviors
•    Discuss the clinical relevance of neuroimmune mechanisms in food allergy–associated anxiety and avoidance behaviors and their implications for patient management
FPIES:
•    Describe the epidemiology and pathophysiology of FPIES
•    Compare FPIES in children and adults
GUT IMMUNE DEFENSES: 
•    Explain how the gut immune system detects harmful dietary components and functions as a food quality control mechanism.
•    Identify key immune pathways involved in sensing food borne toxins and triggering protective physiological and behavioral responses.
•    Describe how immune mediated aversion and avoidance contribute to host defense beyond pathogen elimination.
•    Apply this framework to understand maladaptive responses in food allergy and other gastrointestinal inflammatory disorders.
IMMUNITY:
•    Recognize Inducible laryngospasm/ ILO
•    Distinguish immune drug allergy vs non-immune intolerance
•    Define Multiple Drug Intolerance Syndrome (MDIS) and its common patterns
•    Apply central sensitization and role of neuroplasticity as an A/I-friendly framework
IMMUNOTHERAPY:
•    Compare emerging Allergy Immunotherapy (AIT) modalities
•    Review IntraLymphatic Immunotherpy (ILIT) mechanism + RCT evidence
•    Understand safety, feasibility, and limitations
•    Identify pipeline directions and key research gaps in allergen immunotherapy
MCAS:
•    Review current MCAS diagnostic criteria
•    Examine performance of proposed biomarkers and criteria
•    Evaluate symptom specificity
•    Identify major evidence gaps
TOPICAL STEROID WITHDRAWAL SYNDROME:
•    Differentiate between Topical Steroid Withdrawal (TSW) and atopic dermatitis by utilizing proposed diagnostic criteria
•    Explain the underlying mechanism of TSW and key differences from AD pathogenesis
•    Evaluate potential targeted therapeutic strategies
VOCAL CORD DYSFUNCTION:
•    Distinguish vocal cord dysfunction from asthma and other upper airway disorders, with emphasis on symptoms, history, and laryngoscopic findings
•    Identify clinical scenarios in which referral to an otolaryngologist is appropriate for the diagnosis and management of suspected vocal cord dysfunction
•    Incorporate ENT-directed interventions—such as breathing retraining therapy—into a multidisciplinary treatment plan for patients with vocal cord dysfunction