Symptoms, Diagnosis & Treatment Options for Mast Cell Disorders (AAN)

Price: FREE for members and non-members

Session recorded on September 10, 2025
Speaker: Jonathan Lyons, MD

Despite varying experience levels, physicians encounter patients with mast cell–related symptoms but lack familiarity with the full spectrum of mast cell disorders, leading to underdiagnosis or delayed treatment. Current practice gaps include limited awareness of updated diagnostic criteria, variability in management strategies, and uncertainty around emerging therapies. This activity will address these knowledge shortfalls by providing practical, evidence-based guidance to improve recognition, diagnosis, and care of patients with mast cell disorders.

This program is a collaboration between the American College of Allergy, Asthma & Immunology and the Allergy and Asthma Network (AAN).

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Accreditation
The American College of Allergy, Asthma & Immunology (ACAAI) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Designation
The American College of Allergy, Asthma & Immunology (ACAAI) designates this enduring material for a maximum of 1 AMA PRA Category 1 CreditTM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Target Audience

Primary Care Providers
Allied Health Professionals

Learning Objectives

Upon completion of this activity learners should be able to:
1.    Summarize the key clinical signs and symptoms indicative of mastocytosis, differentiating between cutaneous and systemic forms.
2.    Apply recent research findings and technological innovations to the diagnostic approach for mastocytosis, including molecular and imaging techniques.
3.    Illustrate the mechanisms and clinical applications of new and emerging targeted therapies in the management of systemic mastocytosis.

Additional information
Disclosure: 

As required by the Accreditation Council for Continuing Medical Education (ACCME) and in accordance with the American College of Allergy, Asthma and Immunology (ACAAI) policy, all individuals in a position to control or influence the content of an activity must disclose all financial relationships with any ineligible company that have occurred within the past 24 months. 

Ineligible companies are those whose primary business is producing, marketing, selling, re-selling, or distributing health care products used by or on patients. The ACCME does not consider providers of clinical service directly to patients to be Ineligible Companies. Examples of ineligible companies include: 
 
•    Advertising, marketing, or communication firms whose clients are ineligible companies
•    Bio-medical startups that have begun a governmental regulatory approval process
•    Compounding pharmacies that manufacture proprietary compounds
•    Device manufacturers or distributors
•    Diagnostic labs that sell proprietary products
•    Growers, distributors, manufacturers or sellers of medical foods and dietary supplements
•    Manufacturers of health-related wearable products
•    Pharmaceutical companies or distributors
•    Pharmacy benefit managers
•    Reagent manufacturers or sellers
  
The ACCME does not consider providers of clinical service directly to patients to be commercial interests. For more information, visit www.accme.org. All identified relevant relationships must be mitigated and the educational content thoroughly vetted for fair balance, scientific objectivity, and appropriateness of patient care recommendations. It is required that disclosure of or absence of relevant financial relationships be provided to the learners prior to the start of the activity.

Learners must also be informed when off-label, experimental/investigational uses of drugs or devices are discussed in an educational activity or included in related materials.

Disclosure in no way implies that the information presented is biased or of lesser quality. It is incumbent upon course participants to be aware of these factors in interpreting the program contents and evaluating recommendations. Moreover, expressed views do not necessarily reflect the opinions of the ACAAI. All identified relevant financial relationships with ineligible companies have been mitigated.

Course summary
Available credit: 
  • 1.00 AMA PRA Category 1 Credit™
  • 1.00 Attendance
Course opens: 
09/15/2025
Course expires: 
12/31/2026
Rating: 
0

All identified relevant financial relationships with ineligible companies have been mitigated.

Speaker:
Jonathan Lyons, MD
Advisor: Blueprint Medicines, Cogent
Consultant: Blueprint Medicines, Cogent, Biogen, Visterra

Moderator:
Ruthie Marker, AAN Staff
No relevant financial relationships with ineligible companies to disclose

Lynda Mitchell, AAN Staff, Planner, Moderator - No relevant financial relationships with ineligible companies to disclose
Todd Mahr, MD, Planner, Reviewer: Speaker: AstraZeneca, GSK, Regeneron; Advisor: Regeneron, Sanofi; Consultant: Sanofi
Kenneth Babe, MD, Reviewer - No relevant financial relationships with ineligible companies to disclose
Katy Allen, ACAAI Staff, Reviewer - No relevant financial relationships with ineligible companies to disclose

Available Credit

  • 1.00 AMA PRA Category 1 Credit™
  • 1.00 Attendance
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