Inborn errors of immunity with overlap of allergy and autoimmune disease
Annals of Allergy, Asthma & Immunology
July 2026 Volume 137, Issue 1, Pages 8-16 CME Review
Accreditation: The American College of Allergy, Asthma & Immunology (ACAAI) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Designation: The American College of Allergy, Asthma & Immunology (ACAAI) designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Target Audience
Physicians involved in providing patient care in the field of allergy/asthma/immunology
Learning Objectives
At the conclusion of this activity, participants should be able to:
• Detect variability of clinical and immunologic laboratory features seen in patients with inborn errors of immunity (IEI) associated with atopy and autoimmunity.
• Recommend genetic testing for IEI in patients primarily presenting with atopic or autoimmune features, even in the absence of infectious complications.
Planners:
• Jonathan Spergel, MD, PhD, FACAAIhas no relevant financial relationships with ineligible companies to disclose.
• Kurt Shulenberger, MA, has no relevant financial relationships with ineligible companies to disclose.
Authors:
• Jennifer Heimall, MD, has no relevant financial relationships with ineligible companies to disclose.
Available Credit
- 1.00 AMA PRA Category 1 Credit™
- 1.00 Attendance

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